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  COVID-19 Inflammation Score for Disease Severity


Inflammation Score  

Include literature references: Yes   No

  Inflammation Score Interpretation

0 points: No significant inflammation; 1.1 to 1.8% in-hospital mortality
1 to 2 points: Mild inflammation; 2.8 to 2.9% in-hospital mortality
3 to 4 points: Moderate inflammation; 4.1 to 5.2% in-hospital mortality
5 to 6 points: Severe inflammartion; 12.6 to 13.8% in-hospital mortality

  • This calculator represents findings from the literature referenced below. It is important to understand that these findings may not be representative of the experience in your local healthcare system.
  • Mortality estimates represent data from both derivation and validation cohorts.[1]

Equations used
InflammationScore = AlbuminFactor + HSCRPFactor + WBCFactor


Calculation Details and Variables
  • AlbuminFactor is assigned values by this ordered logic:
    • If Albumin ≤3.6 g/dL AlbuminFactor = 3
    • Else AlbuminFactor = 0.
  • HSCRPFactor is assigned values by this ordered logic:
    • If HS CRP ≥13 mg/L HSCRPFactor = 2
    • Else HSCRPFactor = 0.
  • WBCFactor is assigned values by this ordered logic:
    • If WBC ≥9.3 x10^3/microL WBCFactor = 1
    • Else WBCFactor = 0.

  1. Gonzalez-Pacheco H, Bojalil R, Amezcua-Guerra LM, et al. Derivation and validation of a simple inflammation-based risk score system for predicting in-hospital mortality in acute coronary syndrome patients. J Cardiol. 2019 May;73(5):416-424. PubMed ID: 30600191 PubMed Logo

Associated Medical Subject Headings [MeSH]
         Acute Coronary Syndrome,   Aged,   Biomarkers,   C-Reactive Protein,   Cohort Studies,   Female,   Hospital Mortality,   Humans,   Inflammation,   Leukocyte Count,   Male,   Middle Aged,   Odds Ratio,   Reproducibility of Results,   Risk Factors,   Serum Albumin

Associated Logical Observation Identifiers Names and Codes [LOINC]
Parameter LOINC's and Suggested Units
Albumin 1751-7 : g/dL      
HS CRP 1988-5 : mg/L      30522-7 : mg/L      71426-1 : mg/L      76486-0 : nmol/L      
WBC 6690-2 : #/microL      

This material contains content from LOINC® (http://loinc.org). The LOINC table, LOINC codes, and LOINC panels and forms file are copyright © 1995-2014, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and available at no cost under the license at http://loinc.org/terms-of-use.

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