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Polycythemia Vera Diagnostic Criteria   Diagnostic : 2 Group A and 1 Group B and 0 Group C Diagnostic : 2 Group A and 0 Group B and 2 Group C   Group A       Elevated RBC mass       Males: >= 36mL/kg       Females: >= 32 mL/kg       Arterial O2 saturation >= 92% Group B       Splenomegaly Group C       Platelet count > 400,000/microL       WBC count > 12,000/microL in the absence of fever or infection       Leukocyte alkaline phosphatase (LAP) score > 100 in the absence of fever or infection       B12 > 900 pg/mL or serum unbound B12-binding capacity > 2200 pg/mL               References Berk PD, Goldberg JD, Donovan PB, et. al. Therapeutic recommendations in polycythemia vera based on Polycythemia Vera Study Group protocols. Semin Hematol. 1986 Apr;23(2):132-43.     Legal Notices and Disclaimer   All information contained in and produced by the MedCalc 3000 system is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease. THIS INFORMATION IS NOT INTENDED TO REPLACE CLINICAL JUDGMENT OR GUIDE INDIVIDUAL PATIENT CARE IN ANY MANNER. Click here for full notice and disclaimer.   MedCalc 3000 is Copyright © 1998-2008 Foundation Internet Services, LLC    [Build 237516 v9.1]