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Polycythemia Vera Diagnostic Criteria

 

Diagnostic : 2 Group A and 1 Group B and 0 Group C

Diagnostic : 2 Group A and 0 Group B and 2 Group C
 
Group A
      Elevated RBC mass
      Males: >= 36mL/kg
      Females: >= 32 mL/kg
      Arterial O2 saturation >= 92%
Group B
      Splenomegaly
Group C
      Platelet count > 400,000/microL
      WBC count > 12,000/microL in the absence of fever or infection
      Leukocyte alkaline phosphatase (LAP) score > 100 in the absence of fever or infection
      B12 > 900 pg/mL or serum unbound B12-binding capacity > 2200 pg/mL

 

 
     

 

 
References
  1. Berk PD, Goldberg JD, Donovan PB, et. al. Therapeutic recommendations in polycythemia vera based on Polycythemia Vera Study Group protocols. Semin Hematol. 1986 Apr;23(2):132-43. PubMed Logo

 

 
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