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Endocarditis Diagnostic Criteria -- Duke Criteria

 

Diagnostic : 2 Major Criteria and 0 Minor Criteria

Diagnostic : 1 Major Criteria and 3 Minor Criteria

Diagnostic : 0 Major Criteria and 5 Minor Criteria
 
Major Diagnostic Criteria
      Positive blood culture for typical Infective Endocarditis organisms (strep viridins or bovis, HACEK, staph aureous without other primary site, enterococcus), from 2 separate blood cultures or 2 positive cultures from samples drawn > 12 hours apart, or 3 or a majority of 4 separate cultures of blood (first and last sample drawn 1 hour apart)
      Echocardiogram with oscillating intracardiac mass on valve or supporting structures, in the path of regurgitant jets, or on implanted material in the absence of an alternative anatomic explanation, or abscess, or new partial dehiscence of prosthetic valve or new valvular regurgitation
Minor Diagnostic Criteria
      Predisposing heart condition or intravenous drug use
      Temp > 38.0° C (100.4° F)
      Vascular phenomena: arterial emboli, pulmonary infarcts, mycotic aneurysms, intracranial bleed, conjunctival hemorrhages, Janeway lesions
      Immunologic phenomena: glomerulonephritis, Osler nodes, Roth spots, rheumatoid factor
      Microbiological evidence: positive blood culture but does not meet a major criterion as noted above or serological evidence of active infection with organism consistent with endocarditis (excluding coag neg staph, and other common contaminants)
      Echocardiographic findings: consistent with endocarditis but do not meet a major criterion as noted above

 

 
     

 

 

 
References
  1. Durack DT, Lukes AS, Bright DK. New criteria for diagnosis of infective endocarditis: utilization of specific echocardiographic findings. Duke Endocarditis Service. American Journal of Medicine. 96(3):200-9, 1994. PubMed Logo
  2. Lukes AS, Bright DK, Durack DT. Diagnosis of infective endocarditis. Infect Dis Clin North Am. 1993 Mar;7(1):1-8. Review. PubMed Logo

 
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